Showing posts with label cancer treatment. Show all posts
Showing posts with label cancer treatment. Show all posts
Sunday, September 21, 2008
Lung Cancer: Principles and Practice
By Harvey I Pass, David P Carbone, David H Johnson, John D Minna, Andrew T Turrisi,
Publisher: Lippincott Williams & Wilkins
Number Of Pages: 1000
Publication Date: 2004-12-01
Sales Rank: 639838
ISBN / ASIN: 0781746205
EAN: 9780781746205
Binding: Hardcover
Manufacturer: Lippincott Williams & Wilkins
Studio: Lippincott Williams & Wilkins
Average Rating: 5
Thoroughly revised and updated, this Third Edition is the most comprehensive, current reference on lung cancer, with contributions from the world’s foremost surgeons, radiation oncologists, medical oncologists, pulmonologists, and basic scientists. This edition includes sixteen new chapters and has been reorganized for greater clinical emphasis.
Coverage includes complete information on combined modality treatments for small cell and non-small cell lung cancer and on complications of treatment and management of metastases. Emphasis is also given to early detection, screening, prevention, and new imaging techniques. A new editor, David Carbone, provides state-of-the-art coverage of the molecular genetics and biology of lung cancer.
Review:
Lung cancer- a review
Pass’ book is excellent, well-written, and comprehensive. It is one of the first books patients and family members should go to, though they should be cautioned that the book is written for a medical audience. Skip the first two chapters on mollecular biology which are far too technical, and go to some of the other chapters written in a detailed but comprehensive fashion. This book will prove exceptionally useful, but tough reading for many, so keep a medical dictionary and encylopedia nearby.
Review:
An excellent resource for lung cancer clinicians and patient
This second edition is an excellent, readable resource that makes few assumptions about the reader’s familiarity with lung cancer, molecular biology, or cancer genetics. Contains many entirely new chapters as well as carefully updated material from the first edition. Geared to oncologists and researchers, but nonetheless a good foundation resource for patients and families who wish to learn a great deal about lung cancer and its management.
free medical book
Publisher: Lippincott Williams & Wilkins
Number Of Pages: 1000
Publication Date: 2004-12-01
Sales Rank: 639838
ISBN / ASIN: 0781746205
EAN: 9780781746205
Binding: Hardcover
Manufacturer: Lippincott Williams & Wilkins
Studio: Lippincott Williams & Wilkins
Average Rating: 5
Thoroughly revised and updated, this Third Edition is the most comprehensive, current reference on lung cancer, with contributions from the world’s foremost surgeons, radiation oncologists, medical oncologists, pulmonologists, and basic scientists. This edition includes sixteen new chapters and has been reorganized for greater clinical emphasis.
Coverage includes complete information on combined modality treatments for small cell and non-small cell lung cancer and on complications of treatment and management of metastases. Emphasis is also given to early detection, screening, prevention, and new imaging techniques. A new editor, David Carbone, provides state-of-the-art coverage of the molecular genetics and biology of lung cancer.
Review:
Lung cancer- a review
Pass’ book is excellent, well-written, and comprehensive. It is one of the first books patients and family members should go to, though they should be cautioned that the book is written for a medical audience. Skip the first two chapters on mollecular biology which are far too technical, and go to some of the other chapters written in a detailed but comprehensive fashion. This book will prove exceptionally useful, but tough reading for many, so keep a medical dictionary and encylopedia nearby.
Review:
An excellent resource for lung cancer clinicians and patient
This second edition is an excellent, readable resource that makes few assumptions about the reader’s familiarity with lung cancer, molecular biology, or cancer genetics. Contains many entirely new chapters as well as carefully updated material from the first edition. Geared to oncologists and researchers, but nonetheless a good foundation resource for patients and families who wish to learn a great deal about lung cancer and its management.
free medical book
Friday, September 19, 2008
The Gale Encyclopedia Of Cancer
The Gale Encyclopedia Of Cancer
The Gale Encyclopedia Of Cancer The Gale Encyclopedia Of Cancer Gale Cengage | ISBN: 1414403623 | 1419 pages | PDF | 25,4 MB
Entries on drugs, medical procedures, and therapies are based on the same format. Each begins with the definition, a statement of purpose or use, and a description. Drugs are identified by their chemical formulae and generic and brand names. Dosage information resembles that in the Physician’s Desk Reference but is presented in lay language. Precautions, interactions, side effects, and risks are covered. Medical procedures (therapies and tests) are thoroughly outlined from start to finish, including preparation, risk, and aftercare. Both normal and abnormal results are identified. All types of entries conclude with lists of resources to consult. Usually these are books, periodicals, and organizations. Diagrams and photos from medical texts are peppered throughout the encyclopedia. Several full-skeleton body-system illustrations serve as additional identification aids. An encyclopedia of this caliber would not be complete without lists of support groups, government agencies, research centers, and comprehensive cancer centers. These appear in the appendixes. Three pages of contributors to this encyclopedia, with credentials and affiliations, precede the main text. This outstanding medical resource belongs in public, academic, and medical libraries accessible to patients and their families.
free medical book
The Gale Encyclopedia Of Cancer The Gale Encyclopedia Of Cancer Gale Cengage | ISBN: 1414403623 | 1419 pages | PDF | 25,4 MB
Entries on drugs, medical procedures, and therapies are based on the same format. Each begins with the definition, a statement of purpose or use, and a description. Drugs are identified by their chemical formulae and generic and brand names. Dosage information resembles that in the Physician’s Desk Reference but is presented in lay language. Precautions, interactions, side effects, and risks are covered. Medical procedures (therapies and tests) are thoroughly outlined from start to finish, including preparation, risk, and aftercare. Both normal and abnormal results are identified. All types of entries conclude with lists of resources to consult. Usually these are books, periodicals, and organizations. Diagrams and photos from medical texts are peppered throughout the encyclopedia. Several full-skeleton body-system illustrations serve as additional identification aids. An encyclopedia of this caliber would not be complete without lists of support groups, government agencies, research centers, and comprehensive cancer centers. These appear in the appendixes. Three pages of contributors to this encyclopedia, with credentials and affiliations, precede the main text. This outstanding medical resource belongs in public, academic, and medical libraries accessible to patients and their families.
free medical book
Friday, September 12, 2008
Endosurgery for Cancer
Endosurgery for Cancer
Product Details
»Book Publisher: Landes Bioscience (September, 1999)
»ISBN: 1570595259
»Book author: Steve Eubanks, Ricardo Vitor Cohen, Riad N. Younes, Fredrick Brody
Book Description:
This book provides surgeons with updated information about the current status, perspectives and controversies for staging and treating cancer through minimal access procedures. The authors discuss the biology of, techniques and equipment used for, and the perspectives and controversies surrounding videoendoscopy, in particular, in its application to cancer management.
free medical book
Product Details
»Book Publisher: Landes Bioscience (September, 1999)
»ISBN: 1570595259
»Book author: Steve Eubanks, Ricardo Vitor Cohen, Riad N. Younes, Fredrick Brody
Book Description:
This book provides surgeons with updated information about the current status, perspectives and controversies for staging and treating cancer through minimal access procedures. The authors discuss the biology of, techniques and equipment used for, and the perspectives and controversies surrounding videoendoscopy, in particular, in its application to cancer management.
free medical book
Cancer Cytogenetic
Cancer Cytogenetics: Methods and Protocols (Methods in Molecular Biology)
by John Swansbury (Editor)
Product Details
* Hardcover: 283 pages
* Publisher: Humana Press (April 2003)
* Language: English
* ISBN-10: 1588290808
* ISBN-13: 978-1588290809
Book Description
The Royal Marsden NHS Trust, Surrey, UK. Text describes in detail the key cytogenetic and FISH techniques used in the genetic analysis of human malignancies and how to interpret the results. Each protocol contains novel ideas and time-saving techniques. Also provides guidance on the significance and interpretation of findings.
Book Info
The Royal Marsden NHS Trust, Surrey, UK. Text describes in detail the key cytogenetic and FISH techniques used in the genetic analysis of human malignancies and how to interpret the results. Each protocol contains novel ideas and time-saving techniques. Also provides guidance on the significance and interpretation of findings.
Password:econiches
free medical book
by John Swansbury (Editor)
Product Details
* Hardcover: 283 pages
* Publisher: Humana Press (April 2003)
* Language: English
* ISBN-10: 1588290808
* ISBN-13: 978-1588290809
Book Description
The Royal Marsden NHS Trust, Surrey, UK. Text describes in detail the key cytogenetic and FISH techniques used in the genetic analysis of human malignancies and how to interpret the results. Each protocol contains novel ideas and time-saving techniques. Also provides guidance on the significance and interpretation of findings.
Book Info
The Royal Marsden NHS Trust, Surrey, UK. Text describes in detail the key cytogenetic and FISH techniques used in the genetic analysis of human malignancies and how to interpret the results. Each protocol contains novel ideas and time-saving techniques. Also provides guidance on the significance and interpretation of findings.
Password:econiches
free medical book
Cancer: Principles and Practice of Oncology 6th edit
Vincent T. Devita, Samuel Hellman, Steven A. Rosenberg, "Cancer: Principles and Practice of Oncology" (6th edition)
Lippincott Williams & Wilkins | ISBN 0781722292 | 2001 Year | PDB | 39,6 Mb | 3235 Pages
Acclaimed by the worldwide medical community as the standard-setting oncology reference, Cancer: Principles and Practice of Oncology is now in its Fifth Edition. This new edition has been extensively reorganized to integrate the groundbreaking advances of molecular biology into the broad range of oncologic practice, including cancer prevention, diagnosis, and treatment.A new introductory section -- Essentials of Modern Oncologic Science -- provides a base of information on molecular biology, signal transduction, and immunology. The Principles of Oncology section includes new chapters on the cell cycle and on principles of cancer management related to molecular pathology, cancer genetics, and biologic therapy. The Practice of Oncology section features entirely new chapters on the molecular biology of each organ site, as well as up-to-date multimodality treatment guidelines for each stage of disease. Also included are timely discussions of supportive and palliative care, health care reform, regulatory issues, drug development, gene therapy, and cancer vaccines
Password: www.AvaxHome.ru
free medical book
Lippincott Williams & Wilkins | ISBN 0781722292 | 2001 Year | PDB | 39,6 Mb | 3235 Pages
Acclaimed by the worldwide medical community as the standard-setting oncology reference, Cancer: Principles and Practice of Oncology is now in its Fifth Edition. This new edition has been extensively reorganized to integrate the groundbreaking advances of molecular biology into the broad range of oncologic practice, including cancer prevention, diagnosis, and treatment.A new introductory section -- Essentials of Modern Oncologic Science -- provides a base of information on molecular biology, signal transduction, and immunology. The Principles of Oncology section includes new chapters on the cell cycle and on principles of cancer management related to molecular pathology, cancer genetics, and biologic therapy. The Practice of Oncology section features entirely new chapters on the molecular biology of each organ site, as well as up-to-date multimodality treatment guidelines for each stage of disease. Also included are timely discussions of supportive and palliative care, health care reform, regulatory issues, drug development, gene therapy, and cancer vaccines
Password: www.AvaxHome.ru
free medical book
Wednesday, September 3, 2008
2007 Download Aloes: The genus Aloe (Medicinal and Aromatic Plants - Industrial Profiles, 35)
* Publisher: CRC
* Number Of Pages: 408
* Publication Date: 2004-01-23
* Sales Rank: 1750815
* ISBN / ASIN: 0415306728
* EAN: 9780415306720
* Binding: Hardcover
* Manufacturer: CRC
* Studio: CRC
*
Book Description:
Aloes are a large genus of plants, about 450 species, from sub-Saharan Africa, Madagascar, and parts of Arabia. Many species are widespread in warm or tropical semi-arid regions, yet the distribution of others is limited to a few living in desert or wet mountainous regions. While some species have been adopted as medicinal plants since ancient times and others are used locally in folk medicine, scientists have yet to discover the full biological activity of the many aloe compounds. In order to realize the vast potential of the genus, it is essential to gather the knowledge acquired over the last fifty years into one comprehensive compilation. A landmark publication, Aloes: The genus Aloes reviews all botanical, chemical, biochemical, and medical information as well as commercial applications of aloes. The first part of the book features information on the habitat and taxonomy of aloes, followed by a section on aloe constituents. Part 3 focuses on therapeutic activity and includes chapters on aloe's role in wound healing, skin cancer, and the immune system. The final section is devoted to aloe biology. Chapters are written by accomplished contributors who share their expertise and insight from all areas of academia and industry. Providing a solid foundation for future research, this volume brings together a wealth of information on aloes from a variety of sources, including seldom-recorded folk customs. It is a valuable guide for researchers and professionals in the areas of botany, natural product chemistry, pharmacology, dermatology, and immunology.
* Number Of Pages: 408
* Publication Date: 2004-01-23
* Sales Rank: 1750815
* ISBN / ASIN: 0415306728
* EAN: 9780415306720
* Binding: Hardcover
* Manufacturer: CRC
* Studio: CRC
*
Book Description:
Aloes are a large genus of plants, about 450 species, from sub-Saharan Africa, Madagascar, and parts of Arabia. Many species are widespread in warm or tropical semi-arid regions, yet the distribution of others is limited to a few living in desert or wet mountainous regions. While some species have been adopted as medicinal plants since ancient times and others are used locally in folk medicine, scientists have yet to discover the full biological activity of the many aloe compounds. In order to realize the vast potential of the genus, it is essential to gather the knowledge acquired over the last fifty years into one comprehensive compilation. A landmark publication, Aloes: The genus Aloes reviews all botanical, chemical, biochemical, and medical information as well as commercial applications of aloes. The first part of the book features information on the habitat and taxonomy of aloes, followed by a section on aloe constituents. Part 3 focuses on therapeutic activity and includes chapters on aloe's role in wound healing, skin cancer, and the immune system. The final section is devoted to aloe biology. Chapters are written by accomplished contributors who share their expertise and insight from all areas of academia and industry. Providing a solid foundation for future research, this volume brings together a wealth of information on aloes from a variety of sources, including seldom-recorded folk customs. It is a valuable guide for researchers and professionals in the areas of botany, natural product chemistry, pharmacology, dermatology, and immunology.
Multidisciplinary Treatment for Prostate Cancer (2007)
Publisher:Springer | Language: English | ISBN:9781891483554 | 89 pages | Data: 2007 | PDF | 2 Mb
The prostate cancer field has been changing rapidly over the past two decades since the introduction and widespread use of the prostate-specific antigen (PSA). The increase in the number of cases diagnosed with prostate cancer that occurred as a result of screening necessitated refinements of existing therapies and the development of novel approaches. More recently, a greater appreciation of a role for active surveillance for selected patients has also developed. The primary oncologist should play a central role in helping patients make educated decisions about therapy (to treat or not and what is optimal therapy for the individual patient). The changes in the field have been staggering, and the literature can be confusing. This monograph updates the reader on developments in the field, providing a balanced, state-of-the-art assessment of treatment of early prostate cancer. It updates the reader on established forms of therapy, including external beam radiotherapy (EBRT) and brachytherapy, the evolving role of minimally invasive surgery and combination therapies, and, finally, on future directions. In his chapter, Dr. Mack Roach from the University of California at San Francisco gives us his perspective on the role of brachytherapy in early prostate cancer; in particular, in the area of patient selection. In his comprehensive discussion of external beam radiation, he focuses his attention on trials that have demonstrated that survival and/or biochemical (PSA) control rates are improved with the addition of either short-term or long-term androgen-deprivation therapy (ADT) to EBRT, on trials that have demonstrated that biochemical control rates can be improved with the use of higher doses of radiation, and on the emerging role of three-dimensional conformal radiation or intensity- modulated radiotherapy techniques, which permit the delivery of high doses of radiation safely. Dr. Hu and colleagues from the Brigham and Women’s Hospital review the latest in different techniques for performing radical prostatectomy, including minimally invasive surgery, an increasingly popular approach. Although this is a rapidly evolving field, the oncologist needs to be aware of the latest in these approaches. The next two chapters explore integrated approaches. Dr. Sartor from the Dana-Farber Cancer Institute builds on Dr. Roach’s chapter with a thorough review of the different forms of ADT, the evolving appreciation of side effects of ADT, and the role of ADT in early disease in particular when used in conjunction with radiation. He points out, however, the failure of ADT to provide a benefit when used before surgery. Finally, he discusses the potential role of adjuvant ADT in high-risk patients; currently the subject of clinical trials. Drs. Febbo and George from Duke University review the integration of chemotherapy into early prostate cancer treatment. Many small trials have been conducted, and we await the results of the trials that are well outlined in this chapter. Finally, looking to the future of therapy for prostate cancer, the last chapter reviews some of the agents under investigation, which, if they prove to be efficacious, may find their way into the multimodality management of early disease. It is hoped that this monograph gives the practicing oncologist useful and current information to help guide patients through the difficult decision-making process surrounding the diagnosis of early prostate cancer.
The prostate cancer field has been changing rapidly over the past two decades since the introduction and widespread use of the prostate-specific antigen (PSA). The increase in the number of cases diagnosed with prostate cancer that occurred as a result of screening necessitated refinements of existing therapies and the development of novel approaches. More recently, a greater appreciation of a role for active surveillance for selected patients has also developed. The primary oncologist should play a central role in helping patients make educated decisions about therapy (to treat or not and what is optimal therapy for the individual patient). The changes in the field have been staggering, and the literature can be confusing. This monograph updates the reader on developments in the field, providing a balanced, state-of-the-art assessment of treatment of early prostate cancer. It updates the reader on established forms of therapy, including external beam radiotherapy (EBRT) and brachytherapy, the evolving role of minimally invasive surgery and combination therapies, and, finally, on future directions. In his chapter, Dr. Mack Roach from the University of California at San Francisco gives us his perspective on the role of brachytherapy in early prostate cancer; in particular, in the area of patient selection. In his comprehensive discussion of external beam radiation, he focuses his attention on trials that have demonstrated that survival and/or biochemical (PSA) control rates are improved with the addition of either short-term or long-term androgen-deprivation therapy (ADT) to EBRT, on trials that have demonstrated that biochemical control rates can be improved with the use of higher doses of radiation, and on the emerging role of three-dimensional conformal radiation or intensity- modulated radiotherapy techniques, which permit the delivery of high doses of radiation safely. Dr. Hu and colleagues from the Brigham and Women’s Hospital review the latest in different techniques for performing radical prostatectomy, including minimally invasive surgery, an increasingly popular approach. Although this is a rapidly evolving field, the oncologist needs to be aware of the latest in these approaches. The next two chapters explore integrated approaches. Dr. Sartor from the Dana-Farber Cancer Institute builds on Dr. Roach’s chapter with a thorough review of the different forms of ADT, the evolving appreciation of side effects of ADT, and the role of ADT in early disease in particular when used in conjunction with radiation. He points out, however, the failure of ADT to provide a benefit when used before surgery. Finally, he discusses the potential role of adjuvant ADT in high-risk patients; currently the subject of clinical trials. Drs. Febbo and George from Duke University review the integration of chemotherapy into early prostate cancer treatment. Many small trials have been conducted, and we await the results of the trials that are well outlined in this chapter. Finally, looking to the future of therapy for prostate cancer, the last chapter reviews some of the agents under investigation, which, if they prove to be efficacious, may find their way into the multimodality management of early disease. It is hoped that this monograph gives the practicing oncologist useful and current information to help guide patients through the difficult decision-making process surrounding the diagnosis of early prostate cancer.
Wednesday, August 6, 2008
Download Aloes: The genus Aloe (Medicinal and Aromatic Plants - Industrial Profiles, 35)
* Publisher: CRC
* Number Of Pages: 408
* Publication Date: 2004-01-23
* Sales Rank: 1750815
* ISBN / ASIN: 0415306728
* EAN: 9780415306720
* Binding: Hardcover
* Manufacturer: CRC
* Studio: CRC
*
Book Description:
Aloes are a large genus of plants, about 450 species, from sub-Saharan Africa, Madagascar, and parts of Arabia. Many species are widespread in warm or tropical semi-arid regions, yet the distribution of others is limited to a few living in desert or wet mountainous regions. While some species have been adopted as medicinal plants since ancient times and others are used locally in folk medicine, scientists have yet to discover the full biological activity of the many aloe compounds. In order to realize the vast potential of the genus, it is essential to gather the knowledge acquired over the last fifty years into one comprehensive compilation. A landmark publication, Aloes: The genus Aloes reviews all botanical, chemical, biochemical, and medical information as well as commercial applications of aloes. The first part of the book features information on the habitat and taxonomy of aloes, followed by a section on aloe constituents. Part 3 focuses on therapeutic activity and includes chapters on aloe's role in wound healing, skin cancer, and the immune system. The final section is devoted to aloe biology. Chapters are written by accomplished contributors who share their expertise and insight from all areas of academia and industry. Providing a solid foundation for future research, this volume brings together a wealth of information on aloes from a variety of sources, including seldom-recorded folk customs. It is a valuable guide for researchers and professionals in the areas of botany, natural product chemistry, pharmacology, dermatology, and immunology.
* Number Of Pages: 408
* Publication Date: 2004-01-23
* Sales Rank: 1750815
* ISBN / ASIN: 0415306728
* EAN: 9780415306720
* Binding: Hardcover
* Manufacturer: CRC
* Studio: CRC
*
Book Description:
Aloes are a large genus of plants, about 450 species, from sub-Saharan Africa, Madagascar, and parts of Arabia. Many species are widespread in warm or tropical semi-arid regions, yet the distribution of others is limited to a few living in desert or wet mountainous regions. While some species have been adopted as medicinal plants since ancient times and others are used locally in folk medicine, scientists have yet to discover the full biological activity of the many aloe compounds. In order to realize the vast potential of the genus, it is essential to gather the knowledge acquired over the last fifty years into one comprehensive compilation. A landmark publication, Aloes: The genus Aloes reviews all botanical, chemical, biochemical, and medical information as well as commercial applications of aloes. The first part of the book features information on the habitat and taxonomy of aloes, followed by a section on aloe constituents. Part 3 focuses on therapeutic activity and includes chapters on aloe's role in wound healing, skin cancer, and the immune system. The final section is devoted to aloe biology. Chapters are written by accomplished contributors who share their expertise and insight from all areas of academia and industry. Providing a solid foundation for future research, this volume brings together a wealth of information on aloes from a variety of sources, including seldom-recorded folk customs. It is a valuable guide for researchers and professionals in the areas of botany, natural product chemistry, pharmacology, dermatology, and immunology.
Monday, August 4, 2008
PRINS and In Situ PCR Protocols (Methods in Molecular Biology: Volume 334)
PRINS and In Situ PCR Protocols (Methods in Molecular Biology: Volume 334)
Humana Press | 1588295494 | Edition - 2006-04-01 | PDF | 264 pages | 2.2 MB | rapidshare
This completely revised and updated edition takes advantage of the many new developments and applications that have occurred in PRINS and in situ PCR technology, including a new fast multicolor PRINS method for identifying human chromosomes, PRINS protocols for in situ detection of unique sequences and point mutation analysis, a new dideoxy PRINS procedure, and in situ PCR and PRINS protocols for plants. The authors describe in detail various applications of PRINS in human (detection of gene deletions in cancer detection of fetal cells in maternal blood, and assessment of aneuploidy in brain tissues and embryos) as well as plant cells. Readily reproducible in situ PCR techniques are also presented for the detection of cytomegalovirus, and for use in combination with microdissection. In situ RT-PCR techniques are also given for use in plant or cancer investigation.
Humana Press | 1588295494 | Edition - 2006-04-01 | PDF | 264 pages | 2.2 MB | rapidshare
This completely revised and updated edition takes advantage of the many new developments and applications that have occurred in PRINS and in situ PCR technology, including a new fast multicolor PRINS method for identifying human chromosomes, PRINS protocols for in situ detection of unique sequences and point mutation analysis, a new dideoxy PRINS procedure, and in situ PCR and PRINS protocols for plants. The authors describe in detail various applications of PRINS in human (detection of gene deletions in cancer detection of fetal cells in maternal blood, and assessment of aneuploidy in brain tissues and embryos) as well as plant cells. Readily reproducible in situ PCR techniques are also presented for the detection of cytomegalovirus, and for use in combination with microdissection. In situ RT-PCR techniques are also given for use in plant or cancer investigation.
Checkpoint Controls and Cancer: Volume 2: Activation and Regulation Protocols (Methods in Molecular Biology)
Checkpoint Controls and Cancer: Volume 2: Activation and Regulation Protocols (Methods in Molecular Biology)
* Publisher: Humana Press; 1 edition (June 24, 2004)
* Language: English
* ISBN-10: 1588295001
* ISBN-13: 978-1588295002
Book Description
Prestigious researchers from ten different countries present readily reproducible experimental protocols to study the molecular components of checkpoint controls and their regulation. Described in step-by-step detail, these cutting-edge techniques offer novel approaches, such as the use of genome databases and siRNA, to analyzing how cells of the human body can escape proper surveillance to grow into a tumor. Additional experimental methods are provided for the manipulation of checkpoint pathways and the analysis of the resulting consequences for the cellular phenotype. An earlier first volume, Reviews and Model Systems, comprehensively reviews the complexities of checkpoint controls and the model systems needed to study them.
* Publisher: Humana Press; 1 edition (June 24, 2004)
* Language: English
* ISBN-10: 1588295001
* ISBN-13: 978-1588295002
Book Description
Prestigious researchers from ten different countries present readily reproducible experimental protocols to study the molecular components of checkpoint controls and their regulation. Described in step-by-step detail, these cutting-edge techniques offer novel approaches, such as the use of genome databases and siRNA, to analyzing how cells of the human body can escape proper surveillance to grow into a tumor. Additional experimental methods are provided for the manipulation of checkpoint pathways and the analysis of the resulting consequences for the cellular phenotype. An earlier first volume, Reviews and Model Systems, comprehensively reviews the complexities of checkpoint controls and the model systems needed to study them.
Signal Transduction in Cancer (Cancer Treatment and Research)
Signal Transduction in Cancer (Cancer Treatment and Research)
Springer | 1402073402 | Edition - 2002-12-31 | PDF |336 pages| 6.4 MB | Rapidshare & Megaupload&Aliceinwire
One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously.
This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents.
Series Editor comments:
"The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."
Springer | 1402073402 | Edition - 2002-12-31 | PDF |336 pages| 6.4 MB | Rapidshare & Megaupload&Aliceinwire
One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously.
This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents.
Series Editor comments:
"The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."
Thursday, July 31, 2008
Deoxynucleoside Analogs in Cancer Therapy (Cancer Drug Discovery and Development)
Deoxynucleoside Analogs in Cancer Therapy (Cancer Drug Discovery and Development)
Humana Press | ISBN 1588293270 | Edition - 2006 | PDF | 476 pages | 3.19 MB | Rapidshare & Megaupload&Aliceinwire
Emerging as an important new volume in the renowned Cancer Drug Discovery and Developmentâ„¢ series, Deoxynucleoside Analogs in Cancer Therapy expertly summarizes the current status of development and application of deoxynucleoside analogs. Authoritative up-to-date reviews are presented by scientists well known in their specific areas and all contributions include valuable sound advice on structure and topics.
Organized into several sections, the first part covers general aspects of drug uptake and metabolism and explains how novel technology has enabled a rapid expansion of this field. The second part is concerned with a number of specific drugs including cytarabine, gemcitabine, troxacitabine, clofarabine and ara-G. The final section covers pharmacokinetics, prodrugs, and specific applications such as radiosensitization, gene therapy, and the use of deoxynucleoside analogs as tracers.
Throughout Deoxynucleoside Analogs in Cancer Therapy, the focus is on novel aspects of deoxynucleoside analogs in the clinical context, as well as on unexpected targets of these compounds, such as their specific activity against cell cycle-dependent kinases or oncogenes. The wealth of information presented here can be used to design rational combinations aimed at inhibiting various cellular signaling pathways, or combining inhibition of various targets. Deoxynucleoside Analogs in Cancer Therapy has been designed specifically to facilitate such an interaction between various fields.
Humana Press | ISBN 1588293270 | Edition - 2006 | PDF | 476 pages | 3.19 MB | Rapidshare & Megaupload&Aliceinwire
Emerging as an important new volume in the renowned Cancer Drug Discovery and Developmentâ„¢ series, Deoxynucleoside Analogs in Cancer Therapy expertly summarizes the current status of development and application of deoxynucleoside analogs. Authoritative up-to-date reviews are presented by scientists well known in their specific areas and all contributions include valuable sound advice on structure and topics.
Organized into several sections, the first part covers general aspects of drug uptake and metabolism and explains how novel technology has enabled a rapid expansion of this field. The second part is concerned with a number of specific drugs including cytarabine, gemcitabine, troxacitabine, clofarabine and ara-G. The final section covers pharmacokinetics, prodrugs, and specific applications such as radiosensitization, gene therapy, and the use of deoxynucleoside analogs as tracers.
Throughout Deoxynucleoside Analogs in Cancer Therapy, the focus is on novel aspects of deoxynucleoside analogs in the clinical context, as well as on unexpected targets of these compounds, such as their specific activity against cell cycle-dependent kinases or oncogenes. The wealth of information presented here can be used to design rational combinations aimed at inhibiting various cellular signaling pathways, or combining inhibition of various targets. Deoxynucleoside Analogs in Cancer Therapy has been designed specifically to facilitate such an interaction between various fields.
Somatostatin Analogs in Diagnostics and Therapy
Somatostatin Analogs in Diagnostics and Therapy
Publisher: Landes Bioscience | Language: English | ISBN: 1587062232 | 114 pages | Data: 2007 | PDF | 3 Mb
Somatostatin is a peptide isolated originally from the hypothalamus and considered as an inhibitor of growth hormone secretion. However, further studies have shown that the peptide was ubiquitously distributed and exerts a large spectrum of physiological effects, mostly of an inhibitory nature. The very short half-life of the native peptide limits its therapeutic application. To overcome this limitation the long-lasting modified molecules (analogs) of somatostatin were synthesized. The present book provides comprehensive data on the application of somatostatin analogs in diagnostics and treatment of diseases, mostly endocrine disorders and cancers.
Publisher: Landes Bioscience | Language: English | ISBN: 1587062232 | 114 pages | Data: 2007 | PDF | 3 Mb
Somatostatin is a peptide isolated originally from the hypothalamus and considered as an inhibitor of growth hormone secretion. However, further studies have shown that the peptide was ubiquitously distributed and exerts a large spectrum of physiological effects, mostly of an inhibitory nature. The very short half-life of the native peptide limits its therapeutic application. To overcome this limitation the long-lasting modified molecules (analogs) of somatostatin were synthesized. The present book provides comprehensive data on the application of somatostatin analogs in diagnostics and treatment of diseases, mostly endocrine disorders and cancers.
Directory of Therapeutic Enzymes
Directory of Therapeutic Enzymes
CRC Press | ISBN: 0849327148 | 2005-08-12 | PDF | 312 pages | 9.75 Mb | RS
Carefully crafted to provide tightly focused and authoritative information, the Directory of Therapeutic Enzymes covers all approved therapeutic enzymes currently used in medicine. Written mainly by industry experts, the book includes information sourced directly from the company that developed or manufactured the product. It explores major development issues, from manufacturing and marketing to delivery of the finished product. Chapter 1 reviews applied enzymology while chapter 2 delineates theory and applications. Between them, the first two chapters set the appropriate backdrop for the remaining chapters, which focus on actual enzyme products that have gained regulatory approval for general medical use. The chapter authors discuss the biochemistry of the enzymes, the reactions they catalyze, how they are produced or manufactured, and their medical applications. The book highlights the many applications of approved therapeutic enzymes, including use in the treatment of blood-clotting disorders, certain cancers, and a variety of genetic disorders. Illustrated with tables and figures that support the text, the book is a single source of in-depth technical information.
CRC Press | ISBN: 0849327148 | 2005-08-12 | PDF | 312 pages | 9.75 Mb | RS
Carefully crafted to provide tightly focused and authoritative information, the Directory of Therapeutic Enzymes covers all approved therapeutic enzymes currently used in medicine. Written mainly by industry experts, the book includes information sourced directly from the company that developed or manufactured the product. It explores major development issues, from manufacturing and marketing to delivery of the finished product. Chapter 1 reviews applied enzymology while chapter 2 delineates theory and applications. Between them, the first two chapters set the appropriate backdrop for the remaining chapters, which focus on actual enzyme products that have gained regulatory approval for general medical use. The chapter authors discuss the biochemistry of the enzymes, the reactions they catalyze, how they are produced or manufactured, and their medical applications. The book highlights the many applications of approved therapeutic enzymes, including use in the treatment of blood-clotting disorders, certain cancers, and a variety of genetic disorders. Illustrated with tables and figures that support the text, the book is a single source of in-depth technical information.
Calcium Signalling and Disease: Molcular Pathology of Calcium
Calcium Signalling and Disease: Molcular Pathology of Calcium
Publisher: Kluwer Academic Publishers | Language: English | ISBN: 1402061900 | 608 pages | Data: 2007 | PDF | 4.1 Mb
Description: This topic is a new entry in the area of cellular calcium signaling: yet, it now spans the entire area, with discoveries that cover both genetic and acquired pathologies, even offering glimpses in the direction of therapy. Cellular calcium homeostasis, and thus calcium signalling, is mainly regulated by membrane intrinsic proteins and calcium sensor proteins. Both classes may be involved in pathological processes that affect both human and animals, ranging from common and important diseases (e.g. migraine, diabetes, epilepsia, manic depression, infertility, various types of cancer, Alzheimer’s disease, muscular dystrophy) to rare genetic conditions (e.g., a number of genetic heart conditions, autoimmune retinopathies, night blindness, hereditary amyloid polyneuropathy, malignant hyperthermia, cerebellar ataxia, atherothrombotic disease). Clearly, the topic has now become not only very large, but also very stimulating. Its extensive critical coverage is likely to eventually stimulate fruitful interdisciplinary discussions.
Publisher: Kluwer Academic Publishers | Language: English | ISBN: 1402061900 | 608 pages | Data: 2007 | PDF | 4.1 Mb
Description: This topic is a new entry in the area of cellular calcium signaling: yet, it now spans the entire area, with discoveries that cover both genetic and acquired pathologies, even offering glimpses in the direction of therapy. Cellular calcium homeostasis, and thus calcium signalling, is mainly regulated by membrane intrinsic proteins and calcium sensor proteins. Both classes may be involved in pathological processes that affect both human and animals, ranging from common and important diseases (e.g. migraine, diabetes, epilepsia, manic depression, infertility, various types of cancer, Alzheimer’s disease, muscular dystrophy) to rare genetic conditions (e.g., a number of genetic heart conditions, autoimmune retinopathies, night blindness, hereditary amyloid polyneuropathy, malignant hyperthermia, cerebellar ataxia, atherothrombotic disease). Clearly, the topic has now become not only very large, but also very stimulating. Its extensive critical coverage is likely to eventually stimulate fruitful interdisciplinary discussions.
Proteasomes : The World of Regulatory Proteolysis (Molecular Biology Intelligence Unit)
Publisher:LANDES BIOSCIENCE PUBLISHERS | 2001-02-15 | ISBN 1587060116 | Pages:391 | PDF | 5.5 Mb
This book highlights proteasome structures and how they are related to different aspects of proteasome function. Moreover, the book reports on the functional roles these highly developed proteolytic machines play within the cell. It was a great surprise to the scientific world that proteolysis provides crucial functions in cellular regulation. The surprise was even greater when it was found that not lysosomes, but protease complexes with remarkably sophisticated architectures were responsible for the control of essential regulatory events. Excitingly, proteasomes were found to be involved in widespread functions of cell physiology, which included degradation of protein waste, antigen presentation, regulation of cell metabolism and cell differentiation as well as control of the cell cycle. The discovery of such multiple and essential functions made investigation of proteasome mediated regulatory proteolysis a highly significant theme in cell biology. Written by pioneers in the field the book represents a comprehensive up-to-date view on proteasome structures and functions from the ultimate frontier of cell biology research. It ties the reader to all facets of cell function. This work is an indispensable source for scientists working in the fields of basic and applied cell biology and immunology. Different aspects of proteasome functions are associated with the development of detrimental diseases like cancer, neurodegeneration, cystic fibrosis or immune disorders. Therefore, data reviewed in this book are important for physicians and pharmacologists active in research, and experts in the pharmaceutical industry.
Publisher:LANDES BIOSCIENCE PUBLISHERS | 2001-02-15 | ISBN 1587060116 | Pages:391 | PDF | 5.5 Mb
This book highlights proteasome structures and how they are related to different aspects of proteasome function. Moreover, the book reports on the functional roles these highly developed proteolytic machines play within the cell. It was a great surprise to the scientific world that proteolysis provides crucial functions in cellular regulation. The surprise was even greater when it was found that not lysosomes, but protease complexes with remarkably sophisticated architectures were responsible for the control of essential regulatory events. Excitingly, proteasomes were found to be involved in widespread functions of cell physiology, which included degradation of protein waste, antigen presentation, regulation of cell metabolism and cell differentiation as well as control of the cell cycle. The discovery of such multiple and essential functions made investigation of proteasome mediated regulatory proteolysis a highly significant theme in cell biology. Written by pioneers in the field the book represents a comprehensive up-to-date view on proteasome structures and functions from the ultimate frontier of cell biology research. It ties the reader to all facets of cell function. This work is an indispensable source for scientists working in the fields of basic and applied cell biology and immunology. Different aspects of proteasome functions are associated with the development of detrimental diseases like cancer, neurodegeneration, cystic fibrosis or immune disorders. Therefore, data reviewed in this book are important for physicians and pharmacologists active in research, and experts in the pharmaceutical industry.
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