Biological book Psychiatry

Textbook of Biological Psychiatry - Jaak Panksepp
Book Description
A Textbook of Biological Psychiatry integrates the basic science concerning brain mechanisms of psychiatric disorders alongside surveys of present standard clinical treatment. Organized in a coherent and easy to follow structure, chapters expand across different levels of analysis, from basic mechanisms to clinical practice. This comprehensive reference provides an integrative treatment of the biochemistry of neurotransmission, behavioral pharmacology, and clinical aspects of psychiatric problems including depression, manic-depression, and mood disorders. Other chapters address the biological mechanisms and treatment of depression, anxiety, panic, obsessive-compulsive disorder, and addictions. The editor concludes with a perspective on the future of the field and prospects for understanding and effectively treating mood and anxiety disorders.

Download Book Vetiveria: The Genus Vetiveria (Medicinal & Aromatic Plants- Industrial Profiles)

* Publisher: CRC
* Number Of Pages: 191
* Publication Date: 2002-01-17
* Sales Rank: 2634830
* ISBN / ASIN: 0415275865
* EAN: 9780415275866
* Binding: Hardcover
* Manufacturer: CRC
* Studio: CRC
*

Book Description:

Vetiveria is one of the most versatile genera in plant kingdom. For example, the species Vetiveria zizanoides produces oderous roots from which a precious essential oil is distilled and used in a variety of applications from perfumery to ethnopharmacology. The same roots give the plant particular characteristics that make it a valuable natural barrier against erosion. Vetiveria: The Genus Vetiveria describes the anatomy, physiology, biochemistry, essential oil biogenesis and chemical composition, ethnopharmacology and distillation. The book covers the production of plants for oil exploration, the use of Vetiver as an ecological tool against erosion, flood, soil pollution, and many other applications.

A Manual for Biochemistry Protocols (Manuals in Biomedical Research)"

Markus R. Wenk, Aaron Z. Fernandis, "A Manual for Biochemistry Protocols (Manuals in Biomedical Research)"

World Scientific Publishing Company; 1 Spi edition (March 30, 2007) | ISBN: 9812700668 | 140 pages | PDF | 1,5 Mb

Biochemistry plays an important role in all areas of the biological and medical sciences. With most of the research or diagnosis involved in these areas being based on biochemically obtained observations, it is essential to have a profile of well standardized protocols. This manual is a basic guide for all students, researchers and experts in biochemistry, designed to help readers in directly starting off their experiments without prior knowledge of the protocol. The book dwells on the concepts used in designing the methodologies, thereby giving ample room for researchers to modify them according to their research requirements.

Enzymes in Nonaqueous Solvents: Methods and Protocols (Methods in Biotechnology Volume 15)

Enzymes in Nonaqueous Solvents: Methods and Protocols (Methods in Biotechnology Volume 15)
Humana Press | ISBN:0896039293 | Edition - 2001-01-15 | PDF | 704 pages | 3.21 MB | Rapidshare & Aliceinwire

In Enzymes in Nonaqueous Solvents: Methods and Protocols, leading chemists, biochemists, biotechnologists, and process engineers summarize for the first time a wide range of methods for executing enzymatic transformations under nonaqueous conditions. Each method includes detailed step-by-step instructions for its successful completion, a list of materials, and ancillary notes that explain the scientific basis of the procedure, as well as troubleshooting. Also provided are a generic description of key reactions, advice on biocatalyst preparation, discussion of reaction conditions, and instructions on bioreactor design.
Comprehensive and state-of-the-art, Enzymes in Nonaqueous Solvents: Methods and Protocols offers today's synthetic chemists, biochemists, and process engineers all the essential information needed to carry out enzymatic reactions in nonaqueous media, as well as to successfully scale up to production quantities.

Robin, Ed. Harris, "Cell Biology Protocols "

Robin, Ed. Harris, "Cell Biology Protocols "
John Wiley & Sons; 1 edition (2006) | ISBN:0470847581 | 402 pages | PDF | 13 Mb

As a modern composite scientific discipline, Cell Biology has expanded and moved forward rapidly in recent years. Cell Biologists now require a wide range of techniques, including those of analytical biochemistry and microscopy in all its diverse forms. These are often used alongside the techniques of molecular biology and molecular genetics. This book contains numerous useful protocols, covering light and electron microscopy, cell culture, cell separation, subcellular fractionation, organelle and membrane isolation, and the use of in vitro reassembly systems in Cell Biology. Many of these protocols feature helpful notes and safety information for practical application. The format favours easy use at the bench with space for notes and important safety information. An appendix contains essential analytical information that will prove invaluable to those working on all aspects of cell biology.

This book will be of interest to students and more experienced cell biologists, as well as molecular biologists and those working in genomics and proteomics who are looking for cellular techniques to validate their findings within intact cells.

Hormone Assays in Biological Fluids

Hormone Assays in Biological Fluids
Humana Press | 2006-01-16 | ISBN:1588290050 | 272 pages | pdf | 1.73 Mb
Expert researchers who have developed and applied significant new assays describe in step-by-step detail a variety of methods for measuring a broad variety of hormones, related peptides, and synthetic steroids in various biological fluids. The hormones measured range from glucocorticoids in biological fluids, urinary steroids, aldosterone in blood, and plasma renin activity, to gut hormones in plasma, melatonin, prolactin, 6-sulfatoxymelatonin, and androgens in blood, saliva, and hair. The emphasis is on noncommercial assays so that investigators can set up novel methods suited to their special needs. Commercial assays are also described for comparative purposes. Tutorials on radioimmunoassay, gas chromatography-mass spectrometry, high-performance liquid chromatography, and PCR techniques help the reader to choose the best method for his or her purpose.

Pass: nguyenhuy

Directory of Therapeutic Enzymes

Directory of Therapeutic Enzymes
CRC Press | ISBN: 0849327148 | 2005-08-12 | PDF | 312 pages | 9.75 Mb | RS
Carefully crafted to provide tightly focused and authoritative information, the Directory of Therapeutic Enzymes covers all approved therapeutic enzymes currently used in medicine. Written mainly by industry experts, the book includes information sourced directly from the company that developed or manufactured the product. It explores major development issues, from manufacturing and marketing to delivery of the finished product. Chapter 1 reviews applied enzymology while chapter 2 delineates theory and applications. Between them, the first two chapters set the appropriate backdrop for the remaining chapters, which focus on actual enzyme products that have gained regulatory approval for general medical use. The chapter authors discuss the biochemistry of the enzymes, the reactions they catalyze, how they are produced or manufactured, and their medical applications. The book highlights the many applications of approved therapeutic enzymes, including use in the treatment of blood-clotting disorders, certain cancers, and a variety of genetic disorders. Illustrated with tables and figures that support the text, the book is a single source of in-depth technical information.

Cytokine Inhibitors

Cytokine Inhibitors
CRC Press | ISBN: 0824704347 | 2001-01-15 | PDF | 372 pages | 3.58 Mb | RS
Compiling an up-to-date and detailed survey of the role cytokines play in cell-to-cell communication, development, and differentiation, this comprehensive reference highlights the medical advantages of cytokine inhibition and pursues novel methods of discovery for more potent and specific blocking agents. Investigates the pathogenic role of cytokines and the potential of cytokine inhibitors as anti-inflammatory, anticancer, antiviral agents! Written by 25 recognized experts revealing recent breakthroughs in research, Cytokine Inhibitors · illustrates cases of naturally produced or in vitro engineered polypeptide cytokine blocking agents · describes all possible approaches to cytokine inhibitors, including monoclonal antibodies, soluble receptors, engineered mutant cytokines, and small-molecular-weight receptor antagonists and signaling inhibitors · clearly explains the homeostatic function of cytokine inhibition and verifies therapeutic approaches effecting natural responses in organisms · discusses the results of clinical trials and therapeutic applications of first-generation recombinant receptor antagonists, such as the potential of tumor necrosis factor antagonists as prominent tools in the therapy of chronic inflammatory conditions · concentrates on the clinical development of second-generation small-molecular-weight, orally bioavailable cytokine inhibitors · reviews the improved understanding of intracellular signaling pathways, the structural determinants responsible for cytokine-receptor interaction · lists the three-dimensional structure, relevant receptors, and intracellular tyrosine kinases of cytokines · and much more! Containing over 1400 references as well as tables and drawings, Cytokine Inhibitors serves as an exemplary reference for basic and clinical immunologists; allergists; biochemists; pathologists, hematologists; experimental, cell, and molecular biologists; rheumatologists; infectious disease specialists; medicinal chemists; and medical school and upper-level undergraduate and graduate students in these disciplines.

Carbonic Anhydrase: Its Inhibitors and Activators

Carbonic Anhydrase: Its Inhibitors and Activators
CRC Press | ISBN: 0415306736 | 2005-05-27 | PDF | 376 pages | 8.59 Mb | RS
Carbonic anhydrases (CAs) are metalloenzymes that regulate important physiological functions in organisms throughout the plant and animal kingdoms. These enzymes are found in numerous forms, and in numerous tissues, and present an attractive target for the design of inhibitors and activators with therapeutic value. CA inhibitor-based drugs have been approved for the treatment of glaucoma, and show promise in the areas of oncology, gastroenterology, neurology, nephrology and dermatology; CA activators may prove useful in treating Alzheimer's disease and memory disorders. Carbonic Anhydrase: Its Inhibitors and Activators provides a state-of-the-art overview of the latest developments and challenges in carbonic anhydrase research. Authors describe the mechanisms of action of specific inhibitors in relation to physiological function, and present previously unpublished research on CA activators. Written by a team of internationally recognized experts, this authoritative edition is a leading reference for bioscientists across many disciplines, as well as novices interested in the latest developments in this complex field. An understanding of the mechanisms through which carbonic anhydrases interact with their inhibitors and activators in complex biological environments is essential in developing novel therapeutic agents for the treatment of disease.

Manual for Biochemistry Protocols (Manuals in Biomedical Research)

Markus R. Wenk, Aaron Z. Fernandis, "A Manual for Biochemistry Protocols (Manuals in Biomedical Research)"
World Scientific Publishing Company; 1 Spi edition (March 30, 2007) | ISBN: 9812700668 | 140 pages | PDF | 1,5 Mb

Biochemistry plays an important role in all areas of the biological and medical sciences. With most of the research or diagnosis involved in these areas being based on biochemically obtained observations, it is essential to have a profile of well standardized protocols. This manual is a basic guide for all students, researchers and experts in biochemistry, designed to help readers in directly starting off their experiments without prior knowledge of the protocol. The book dwells on the concepts used in designing the methodologies, thereby giving ample room for researchers to modify them according to their research requirements.

Creatine and Creatine Kinase in Health and Disease

Creatine and Creatine Kinase in Health and Disease
Publisher: Springer | Language: English | ISBN:1402064853 | 450 pages | Data: 2007 | Format: PDF | 2.8 Mb

Description: Although creatine was discovered already in the 1830s, it is only in recent years that its crucial role for human health and general well-being has been increasingly realized and appreciated. A number of beneficial health effects have been ascribed to oral creatine supplementation, such as neuroprotective, ergogenic, anti-diabetic, anti-inflammatory, antiviral, or antitumor effects. Creatine may even improve memory and intelligence. In the present book, emphasis is placed on the intricate interplay between creatine and creatine kinase function on one hand, and proper brain function, neurodegenerative disease and/or neuroprotection on the other hand.The book also elaborates on the recently identified inborn errors of creatine biosynthesis and transport, the so-called cerebral creatine deficiency syndromes. The clinical hallmarks of these disorders are mental retardation, epilepsy, autistic-like behaviour, and speech and language delay. In addition, the muscle growth- and strength-promoting effects, the pharmacokinetics and the safety of oral creatine supplementation are discussed. Finally, the present book outlines the emerging "systems biology" approaches for understanding the ...

Frontiers in Research of the Renin-Angiotensin System on Human Disease

Frontiers in Research of the Renin-Angiotensin System on Human Disease
Publisher: Springer | Language: English | ISBN:1402063718 | 465 pages | Data: 2007 | PDF | 2.5 Mb

Description: The significant impact of the renin-angiotensin system (RAS) on basic research and its clinical relevance are reflected by the flourishing publication of original and review research articles; by the appearance of whole issues of journals dedicated to the RAS; and by specialist books on the RAS. In such a rapidly evolving environment, publications that span the spectrum from basic research to the bedside, fill a particularly valuable niche for clinicians and researchers alike. The primary aim of this book is to provide a topical and timely forum for the critical appraisal of an area of RAS research that is expanding rapidly. In this respect, a collection of thirteen chapters from distinguished and world-class experts in the field has been presented on the contemporary research of the RAS and their implications in human disease. It is clear that outstanding and stellar work on the novel roles of local RAS and their potential clinical application is being done in laboratories and clinics across the globe. This volume should be of general interest to the readership of our "Proteases in Biology and Disease" book series, as well as being a comprehensive book for basic scientists, clinicians and newcomers to this field.

Proteolytic Enzymes: A Practical Approach

Proteolytic Enzymes: A Practical Approach
Oxford University Press, USA | 019963663X | Edition - 2001-03-15 | PDF |358 pages| 30.6 MB | rapidshare & Megaupload&Aliceinwire

Like the popular first edition, this new edition of Proteolytic Enzymes emphasizes practical aspects of the handling, characterization, inhibition, and use of proteolytic enzymes giving general advice and specific examples. The text and protocols have been thoroughly updated to take account of the advances made in the last 10 years in both the increased understanding of the role of peptidases in many critical cellular processes e.g. apoptosis and new technological developments e.g. in recombinant protein expression, protein sequencing, and structural studies. The topics covered are: nomenclature and classification; purification; assay methods; determination of mechanism; inhibition and prevention of unwanted proteolytic activity; characterizing natural inhibitors; proteolytic enzymes in peptide mapping and primary structure elucidation by mass spectrometry and Edman sequencing; limited proteolysis as a structural probe; synthetic function. This book will be as invaluable as the first edition in providing ideas and protocols for scientists either studying proteases or using proteases as a research tool.]

Enzymes in Nonaqueous Solvents: Methods and Protocols (Methods in Biotechnology Volume 15)

Enzymes in Nonaqueous Solvents: Methods and Protocols (Methods in Biotechnology Volume 15)
Humana Press | ISBN:0896039293 | Edition - 2001-01-15 | PDF | 704 pages | 3.21 MB | Rapidshare & Aliceinwire

In Enzymes in Nonaqueous Solvents: Methods and Protocols, leading chemists, biochemists, biotechnologists, and process engineers summarize for the first time a wide range of methods for executing enzymatic transformations under nonaqueous conditions. Each method includes detailed step-by-step instructions for its successful completion, a list of materials, and ancillary notes that explain the scientific basis of the procedure, as well as troubleshooting. Also provided are a generic description of key reactions, advice on biocatalyst preparation, discussion of reaction conditions, and instructions on bioreactor design.
Comprehensive and state-of-the-art, Enzymes in Nonaqueous Solvents: Methods and Protocols offers today's synthetic chemists, biochemists, and process engineers all the essential information needed to carry out enzymatic reactions in nonaqueous media, as well as to successfully scale up to production quantities.

Enzymes in Nonaqueous Solvents: Methods and Protocols (Methods in Biotechnology Volume 15)

Enzymes in Nonaqueous Solvents: Methods and Protocols (Methods in Biotechnology Volume 15)
Humana Press | ISBN:0896039293 | Edition - 2001-01-15 | PDF | 704 pages | 3.21 MB | Rapidshare & Aliceinwire

In Enzymes in Nonaqueous Solvents: Methods and Protocols, leading chemists, biochemists, biotechnologists, and process engineers summarize for the first time a wide range of methods for executing enzymatic transformations under nonaqueous conditions. Each method includes detailed step-by-step instructions for its successful completion, a list of materials, and ancillary notes that explain the scientific basis of the procedure, as well as troubleshooting. Also provided are a generic description of key reactions, advice on biocatalyst preparation, discussion of reaction conditions, and instructions on bioreactor design.
Comprehensive and state-of-the-art, Enzymes in Nonaqueous Solvents: Methods and Protocols offers today's synthetic chemists, biochemists, and process engineers all the essential information needed to carry out enzymatic reactions in nonaqueous media, as well as to successfully scale up to production quantities.

Alkaliphiles: Genetic Properties and Applications of Enzymes

Alkaliphiles: Genetic Properties and Applications of Enzymes
Publisher: Springer | Language: English | ISBN:354033372X | 270 pages | Data: 2006 | PDF | 11 Mb

The pioneering work of Dr. Koki Horikoshi on the discovery, research and applications of alkaliphilic bacteria are described here in their entirety. The isolation, distribution and taxonomy of alkaliphilic microorganisms as well as their cell structure and physiology are discussed for a basic understanding of these entities. The molecular biology and genome sequencing of some alkaliphilic bacterial strains are also presented.

Part II of the volume focuses on enzymes of alkaliphiles and their applications. These include alkaline proteases, starch-degrading enzymes and numerous others. Some of these enzymes are currently in wide commercial use as laundry detergent additives and in wastewater treatment.

Alkaliphiles are a relatively recent field of research that will no doubt provide avenues to a wide range of further discoveries and applications for a new generation of workers in bioscience and technology.

Calcium Signalling and Disease: Molcular Pathology of Calcium

Calcium Signalling and Disease: Molcular Pathology of Calcium
Publisher: Kluwer Academic Publishers | Language: English | ISBN: 1402061900 | 608 pages | Data: 2007 | PDF | 4.1 Mb

Description: This topic is a new entry in the area of cellular calcium signaling: yet, it now spans the entire area, with discoveries that cover both genetic and acquired pathologies, even offering glimpses in the direction of therapy. Cellular calcium homeostasis, and thus calcium signalling, is mainly regulated by membrane intrinsic proteins and calcium sensor proteins. Both classes may be involved in pathological processes that affect both human and animals, ranging from common and important diseases (e.g. migraine, diabetes, epilepsia, manic depression, infertility, various types of cancer, Alzheimer’s disease, muscular dystrophy) to rare genetic conditions (e.g., a number of genetic heart conditions, autoimmune retinopathies, night blindness, hereditary amyloid polyneuropathy, malignant hyperthermia, cerebellar ataxia, atherothrombotic disease). Clearly, the topic has now become not only very large, but also very stimulating. Its extensive critical coverage is likely to eventually stimulate fruitful interdisciplinary discussions.

Peroxiredoxin Systems: Structures and Functions

Peroxiredoxin Systems: Structures and Functions
Publisher: Springer | Language: English | ISBN:1402060505 | 410 pages | Data: 2007 | PDF | 5 Mb

Description: The peroxiredoxins represent an important emerging family of sulfhydryl-linked antioxidant proteins, apparently ubiquitously present in all known organisms. The antioxidant function of the peroxiredoxins complements that of other enzymic and non-enzymic systems within the cell. In addition, there is increasing evidence that the peroxiredoxins play a role in cell signalling, by controlling and/or sensing hydrogen peroxide and peroxynitrite levels. In this, the first book containing a broad survey on the peroxiredoxins, the editors succeeded to involve almost all groups that contributed significant insights into the emerging field. The diverse biological roles of the new protein family are discussed in the context of other antioxidant systems like those based on heme or selenium catalysis. Finally, related future perspectives, which range from antimicrobial therapy up to the understanding of human development and carcinogenesis, are highlighted. Specifically, the book will be of outstanding interest to researchers who want to understand how micro-organisms, plants and animals cope with oxidative stress and how such stress is recognized and linked to adaptive responses via redox regulation of cellular processes.

Springer Handbook of Enzymes, vol.38 - Class 2 Transferases XI: EC 2.7.6 - 2.7.7

Springer Handbook of Enzymes, vol.38 - Class 2 Transferases XI: EC 2.7.6 - 2.7.7
Publisher: Springer | Language: English | ISBN:3540715258 | 569pages | Data: 2007 | PDF | 2 Mb

Description: The objective of the “Springer Handbook of Enzymes” is to provide in concise form data on enzymes sufficiently well characterized. Data sheets are arranged in their EC-Number sequence. The volumes are arranged according to enzyme classes. Considerable progress has been made in enzymology since the publication of the first edition (published as “Enzyme Handbook”): many enzymes are newly classified or reclassified. In the 2nd edition each entry is correlated with references and one or more source organisms. New datafields are created: “application” and “engineering” (for the properties of enzymes where the sequence has been changed). Altogether the amount of data has doubled so that the 2nd edition will consist of 39 volumes plus synonym index. This collection is an indispensable source of information for researchers in biochemistry, biotechnology, organic and analytical chemistry, and food sciences.

Springer Handbook of Enzymes, vol.36 - Class 2 Transferases IX: EC 2.7.1.38 - 2.7.1.112
Publisher: Springer | Language: English | ISBN:3540478078 | 624 pages | Data: 2007 | PDF | 21 Mb

Description: The objective of the “Springer Handbook of Enzymes” is to provide in concise form data on enzymes sufficiently well characterized. Data sheets are arranged in their EC-Number sequence. The volumes are arranged according to enzyme classes. Considerable progress has been made in enzymology since the publication of the first edition (published as “Enzyme Handbook”): many enzymes are newly classified or reclassified. In the 2nd edition each entry is correlated with references and one or more source organisms. New datafields are created: “application” and “engineering” (for the properties of enzymes where the sequence has been changed). Altogether the amount of data has doubled so that the 2nd edition will consist of 39 volumes plus synonym index. This collection is an indispensable source of information for researchers in biochemistry, biotechnology, organic and analytical chemistry, and food sciences.